Wasatch BioLabs has exclusive access to a technology that enables targeted sequencing at up to 2,000 regions of interest, enrichment of 400-2300x, and depth that can be scaled according to researchers' needs. This technology has opened the floodgates for other targeted applications of Oxford Nanopore sequencing and has led to the release of our Targeted DNA Methylation Sequencing Service.
Nanopore technology enables native strand sequencing, which preserves DNA and RNA modifications. We currently offer services that detect DNA methylation (5mC) and hydroxymethylation (5hmC). Oxford Nanopore Technologies is continuously updating the DNA and RNA modifications their technology can detect. We plan on making these additional modifications available for detection in future updates.
Our targeted sequencing services are currently being leveraged in diagnostic screenings for fertility, neurodegenerative disease, cancer, women’s health, autoimmune disease, forensics, and more. If you’re interested in using this technology for your own clinical diagnostic test, contact us to learn more.